Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA7 | P43166 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | CA5A | P35218 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethiazide SCHEMBL122238 | 1.00 | TDP1 (1.00) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL29925887 | 0.90 | TDP1 (0.82) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL13685945 | 0.88 | TDP1 (0.79) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL11038368 | 0.87 | TDP1 (0.77) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| Buthiazide SCHEMBL29364486 | 0.86 | TDP1 (0.76) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL13685954 | 0.86 | TDP1 (0.76) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| Buthiazide SCHEMBL309110 | 0.86 | TDP1 (0.76) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL8972490 | 0.85 | TDP1 (0.74) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL7366786 | 0.84 | TDP1 (0.72) | TDP1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL9810161 | 0.83 | TDP1 (0.71) | TDP1LMNAALDH1A1CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096006-A1 | SYSTEM AND METHOD OF MANIFOLD KERNELIZATION OF MOLECULAR SURFACE | PURDUE RESEARCH FOUNDATION (US) | 2025-05-08 | — | — | WO | disclosed |
| US-20250066790-A1 | ANTISENSE OLIGONUCLEOTIDES FOR MODIFYING PROTEIN EXPRESSION | UNIVERSITY OF ROCHESTER | 2025-02-27 | — | — | US | disclosed |
| CN-116836130-B | Synthesis method of 3, 4-dihydrobenzothiadiazine compound | 嘉实（湖南）医药科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116836130-A | Synthesis method of 3, 4-dihydrobenzothiadiazine compound | 嘉实（湖南）医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |