Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 4/20 | 0.50 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 5/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21664291 | 1.00 | ENPP1 (0.50) | ENPP1KHKPRKDCAURKAAURKB | |
| SCHEMBL25551815 | 0.96 | ENPP1 (0.50) | ENPP1KHKPRKDCAURKAAURKB | |
| SCHEMBL21664290 | 0.93 | ENPP1 (0.52) | ENPP1KHKPRKDCAURKAAURKB | |
| SCHEMBL25552086 | 0.92 | ENPP1 (0.53) | ENPP1KHKPRKDCAURKAAURKB | |
| SCHEMBL21664327 | 0.89 | ENPP1 (0.49) | ENPP1KHKPRKDCAURKAAURKB | |
| SCHEMBL21664420 | 0.89 | ENPP1 (0.49) | ENPP1PRKDCAURKAAURKBPDE3A | |
| SCHEMBL30562896 | 0.89 | ENPP1 (0.49) | ENPP1PRKDCAURKAAURKBPDE3A | |
| SCHEMBL21664421 | 0.87 | ENPP1 (0.49) | ENPP1PRKDCAURKAAURKBPDE3A | |
| SCHEMBL21664259 | 0.87 | ENPP1 (0.47) | ENPP1PRKDCPDE3A | |
| SCHEMBL25551951 | 0.86 | ENPP1 (0.52) | ENPP1KHKPRKDCAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551188-B1 | SUBSTITUTED QUINAZOLINE SULFONAMIDES AS THIOREDOXIN INTERACTING PROTEIN (TXNIP) INHIBITORS | SOUTHERN RES INST (US) | 2023-10-18 | — | — | EP | disclosed |