Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25532412 | 1.00 | ELANE (0.35) | ELANECCNE2CDK1CDK4CCNB1 | |
| SCHEMBL30564356 | 0.82 | CCNE2 (0.32) | ELANECCNE2CDK1CDK4CCNB1 | |
| SCHEMBL30564491 | 0.80 | CCNE2 (0.35) | ELANECCNE2CDK1CDK4CCNB1 | |
| SCHEMBL30564440 | 0.79 | CCNE2 (0.34) | ELANECCNE2CDK1CDK4CCNB1 | |
| SCHEMBL23887012 | 0.77 | CSNK2A2 (0.40) | ELANECCNE2CDK1CDK4CCNB1 | |
| SCHEMBL30564381 | 0.77 | ELANE (0.34) | ELANE | |
| SCHEMBL25532416 | 0.75 | SIRT2 (0.30) | SIRT2 | |
| SCHEMBL30564360 | 0.75 | MAPT (0.39) | GAAALDH1A1MAPTKMT2A | |
| SCHEMBL23887043 | 0.73 | SIRT2 (0.39) | CCNE2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL23886987 | 0.73 | SIRT2 (0.56) | CCNE2CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715658-A | Benzocyclic ketone derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-09-08 | — | — | CN | disclosed |