Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24679204 | 0.86 | PIK3CA (0.73) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30193361 | 0.86 | PIK3CA (0.73) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL29139170 | 0.86 | PIK3CA (0.73) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL25181877 | 0.86 | PIK3CA (0.57) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL25178200 | 0.85 | PIK3CA (0.62) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30564373 | 0.85 | PIK3CA (0.55) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL25185652 | 0.83 | PIK3CA (0.64) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30564396 | 0.79 | PIK3CA (0.72) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30564403 | 0.79 | CCNE2 (0.32) | — | |
| SCHEMBL23895857 | 0.77 | PIK3CA (0.61) | PIK3CAPIK3CBMTORPRKDCPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715658-A | Benzocyclic ketone derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-09-08 | — | — | CN | disclosed |