Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857404 | 0.85 | KDM1A (0.34) | S1PR5BACE1KDM1AMAOBNPC1 | |
| SCHEMBL9896982 | 0.82 | BACE1 (0.35) | S1PR5BACE1KDM1AMAOB | |
| SCHEMBL9896984 | 0.82 | BACE1 (0.35) | S1PR5BACE1KDM1AMAOB | |
| SCHEMBL16224095 | 0.82 | BACE1 (0.35) | S1PR5BACE1KDM1AMAOB | |
| SCHEMBL4356106 | 0.81 | KDM1A (0.43) | KDM1AMAOBGAABTKNPC1 | |
| SCHEMBL4356105 | 0.81 | KDM1A (0.43) | KDM1AMAOBGAABTKNPC1 | |
| SCHEMBL19857373 | 0.80 | KDM1A (0.33) | BACE1KDM1AMAOB | |
| SCHEMBL19857376 | 0.80 | KDM1A (0.33) | BACE1KDM1AMAOB | |
| SCHEMBL4354026 | 0.79 | ACACB (0.34) | KDM1AMAOBBTK | |
| SCHEMBL14631539 | 0.78 | BACE1 (0.38) | BACE1CNR1KDM1AMAOBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4493554-A1 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-01-22 | — | — | EP | disclosed |
| WO-2023178181-A1 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-09-21 | — | — | WO | disclosed |