SCHEMBL30565196

SCHEMBL30565196

CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)[C@@H](N)CCCNC(N)=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
GAA P10253 1/20 0.53
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
NOD1 Q9Y239 2/20 0.43
TDP1 Q9NUW8 5/20 0.43
C3AR1 Q16581 1/20 0.41
ATM Q13315 2/20 0.41
MMP1 P03956 1/20 0.40
MMP3 P08254 1/20 0.40
MMP9 P14780 1/20 0.40
POLB P06746 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
CTSS P25774 1/20 0.40
CTSK P43235 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30898863 0.94 MEN1 (0.56) MEN1KMT2AGAAMAOAMAOB
SCHEMBL30532183 0.92 MEN1 (0.53) MEN1KMT2AGAAMAOAMAOB
SCHEMBL30340151 0.90 MEN1 (0.51) MEN1KMT2AGAAMAOAMAOB
SCHEMBL31384523 0.90 MEN1 (0.51) MEN1KMT2AGAAMAOAMAOB
SCHEMBL30000512 0.87 MEN1 (0.51) MEN1KMT2AGAAMAOAMAOB
SCHEMBL30545028 0.86 MEN1 (0.50) MEN1KMT2AGAAMAOAMAOB
SCHEMBL19971934 0.86 MEN1 (0.53) MEN1KMT2AGAAMAOAMAOB
SCHEMBL30000222 0.86 MEN1 (0.52) MEN1KMT2AGAAMAOAMAOB
SCHEMBL31347317 0.86 MEN1 (0.47) MEN1KMT2AGAAMAOAMAOB
SCHEMBL31264466 0.86 MEN1 (0.47) MEN1KMT2AGAAMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025083205-A1 DRUG COMBINATION COMPRISING ANTI-CD37 ANTIBODY MAYTANSINE CONJUGATE AND BCL2 INHIBITOR OR PI3K INHIBITOR DEBIOPHARM INTERNATIONAL S.A. (CH) 2025-04-24 WO disclosed
EP-4507734-A1 LIGAND-DRUG-CONJUGATES WITH IMPROVED PHARMACOKINETIC AND DRUG RELEASE PROPERTIES Debiopharm Research & Manufacturing S.A. (CH) 2025-02-19 EP disclosed
WO-2023198884-A1 LIGAND-DRUG-CONJUGATES WITH IMPROVED PHARMACOKINETIC AND DRUG RELEASE PROPERTIES DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) 2023-10-19 WO disclosed