Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.34 |
| ▸ | JAK3 | P52333 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
| ▸ | PAK4 | O96013 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | PRKACA | P17612 | 2/20 | 0.32 |
| ▸ | FLT1 | P17948 | 2/20 | 0.32 |
| ▸ | LTK | P29376 | 2/20 | 0.32 |
| ▸ | GRK5 | P34947 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619412 | 0.74 | RPS6KB1 (0.43) | AURKASMN1; SMN2AURKBRPS6KB1 | |
| SCHEMBL2938674 | 0.73 | JAK2 (0.54) | JAK2JAK3PRKD3MAP4K4PAK4 | |
| SCHEMBL3917460 | 0.67 | AKT2 (0.65) | JAK2PRKACASMN1; SMN2MAPTLMNA | |
| SCHEMBL7027575 | 0.67 | ITK (0.48) | AURKARETKDRGSK3BMEN1 | |
| SCHEMBL16619167 | 0.67 | RPS6KB1 (0.38) | JAK2JAK3AURKADAPK3PRKD3 | |
| SCHEMBL18486378 | 0.66 | TOP2A (0.49) | MAPK1LIMK1EGFR | |
| SCHEMBL18486229 | 0.66 | PARP1 (0.34) | JAK2PIM1HTTSMN1; SMN2MEN1 | |
| SCHEMBL27824941 | 0.65 | CYP3A4 (0.61) | ALOX5ALDH1A1MAPTNISCH | |
| SCHEMBL4071205 | 0.65 | AKT2 (0.42) | JAK2JAK3MAP4K4PRKACARPS6KA3 | |
| SCHEMBL3928813 | 0.65 | AKT2 (0.67) | MAP4K4PRKACALRRK2CDK8AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116675691-A | Perylene-based nitrogen-containing organic derivative, modified resin, preparation method, composite material and application | 西南科技大学 | 2023-09-01 | — | — | CN | claimed |
| CN-116675691-A | Perylene-based nitrogen-containing organic derivative, modified resin, preparation method, composite material and application | 西南科技大学 | 2023-09-01 | — | — | CN | disclosed |