Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697572 | 0.70 | NOTUM (0.40) | KMT2AHTR2AHTR2CALDH1A1KDM4E | |
| SCHEMBL20777930 | 0.69 | NOTUM (0.39) | KMT2AHTR2AHTR2CALDH1A1KDM4E | |
| SCHEMBL20777927 | 0.67 | PIM1 (0.39) | KMT2AHTR2AHTR2CADRA2AL3MBTL1 | |
| SCHEMBL10831865 | 0.65 | HTR2A (0.39) | KMT2AHTR2AHTR2CALDH1A1KDM4E | |
| SCHEMBL10289862 | 0.63 | CYP2D6 (0.49) | KMT2AHTR2AHTR2CALDH1A1KDM4E | |
| SCHEMBL9259549 | 0.63 | HTR2A (0.44) | KMT2AHTR2AHTR2CDAOL3MBTL1 | |
| SCHEMBL3243714 | 0.63 | KMT2A (0.38) | KMT2AHTR2AHTR2CALDH1A1KDM4E | |
| SCHEMBL28345272 | 0.63 | NOTUM (0.40) | KMT2AHTR2AHTR2CALDH1A1KDM4E | |
| SCHEMBL13403405 | 0.63 | NOTUM (0.47) | HTR2AHTR2CNOTUMSIGMAR1 | |
| SCHEMBL235219 | 0.62 | NOTUM (0.59) | HTR2AHTR2CNOTUMSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589468-B | Green and mild trifluoro/difluoro methylation pyrrolo [1,2-a ] indole synthesis method | 赣南医学院 | 2024-07-26 | — | — | CN | disclosed |
| CN-116589468-A | Green and mild trifluoro/difluoro methylation pyrrolo [1,2-a ] indole synthesis method | 赣南医学院 | 2023-08-15 | — | — | CN | disclosed |