Sugi Predict

Sugi Predict / Compounds / SCHEMBL30567729

SCHEMBL30567729

SCHEMBL30567729

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@@H](N)CCC(N)=O)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)[C@@H](C)O)[C@@H](C)O

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 1/20 0.68
▸ NPY2R P49146 1/20 0.68
▸ NPY4R P50391 1/20 0.68
▸ NPY5R Q15761 1/20 0.68
▸ GLP1R P43220 16/20 0.62
▸ GIPR P48546 6/20 0.62
▸ CXCR4 P61073 2/20 0.62
▸ CCKBR P32239 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31182980 0.94 NPY1R (0.65) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29679866 0.92 NPY1R (0.72) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30567765 0.92 CXCR4 (0.64) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30906385 0.91 NPY2R (0.71) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30262217 0.91 CXCR4 (0.66) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL31148836 0.91 CALCR (0.70) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29352195 0.91 NPY2R (0.70) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30906461 0.90 NPY1R (0.68) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30862309 0.90 CXCR4 (0.68) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30906422 0.90 NPY1R (0.68) NPY1RNPY2RNPY4RNPY5RGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 — — US disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 — — US disclosed
CN-116601290-A Human chimeric antigen receptor neutrophils, compositions, kits and methods of use 普渡研究基金会 2023-08-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 NPY1R 2969/4885NPY2R 3831/4885NPY4R 3873/4885
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 NPY1R 2969/4885NPY2R 3831/4885NPY4R 3873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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