Sugi Predict

Sugi Predict / Compounds / SCHEMBL30567733

SCHEMBL30567733

SCHEMBL30567733

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H](N)CCC(=O)O)C(=O)NCC(=O)O

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CALCR P30988 3/20 0.57
▸ GLP1R P43220 3/20 0.57
▸ CCKBR P32239 1/20 0.57
▸ TFPI P10646 1/20 0.56
▸ CRHR1 P34998 1/20 0.56
▸ CRHR2 Q13324 1/20 0.56
▸ VIPR1 P32241 1/20 0.55
▸ BACE1 P56817 1/20 0.54
▸ PTH1R Q03431 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30567786 0.95 TFPI (0.58) CALCRGLP1RCCKBRTFPICRHR1
SCHEMBL30436623 0.91 VIPR1 (0.63) CALCRGLP1RCCKBRTFPICRHR1
SCHEMBL31575683 0.91 VIPR1 (0.61) CALCRGLP1RCCKBRCRHR1CRHR2
SCHEMBL31182868 0.90 VIPR2 (0.61) CALCRGLP1RCCKBRTFPICRHR1
SCHEMBL30432376 0.89 TFPI (0.68) GLP1RCCKBRTFPIVIPR1PTH1R
SCHEMBL30567445 0.89 TFPI (0.61) GLP1RTFPIVIPR1
SCHEMBL30437371 0.87 CALCR (0.62) CALCRGLP1RCCKBRTFPICRHR1
SCHEMBL30437143 0.87 BACE1 (0.64) CALCRTFPIVIPR1BACE1PTH1R
SCHEMBL31318943 0.87 GLP1R (0.65) GLP1RCCKBRTFPIVIPR1PTH1R
SCHEMBL30658251 0.87 GLP1R (0.64) GLP1RCCKBRTFPIVIPR1PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 — — US disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 — — US disclosed
CN-116601290-A Human chimeric antigen receptor neutrophils, compositions, kits and methods of use 普渡研究基金会 2023-08-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 CALCR 889/4885GLP1R 2288/4885CCKBR 2620/4885
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 CALCR 889/4885GLP1R 2288/4885CCKBR 2620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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