Sugi Predict

Sugi Predict / Compounds / SCHEMBL30567752

SCHEMBL30567752

SCHEMBL30567752

CC[C@H](C)[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)CC)[C@@H](C)CC)C(C)C)C(C)C)C(C)C

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ VIPR1 P32241 4/20 0.59
▸ TFPI P10646 1/20 0.58
▸ VIPR2 P41587 6/20 0.56
▸ NPY2R P49146 7/20 0.55
▸ NPY4R P50391 7/20 0.55
▸ NPY5R Q15761 7/20 0.55
▸ NPY1R P25929 5/20 0.55
▸ KISS1R Q969F8 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30432741 0.90 VIPR1 (0.62) VIPR1TFPIVIPR2NPY2RNPY4R
SCHEMBL30827583 0.90 NPY4R (0.59) VIPR1TFPINPY2RNPY4RNPY5R
SCHEMBL30483686 0.89 VIPR2 (0.48) VIPR1TFPIVIPR2NPY2RNPY4R
SCHEMBL30712970 0.89 VIPR1 (0.65) VIPR1TFPIVIPR2
SCHEMBL29835241 0.88 NPY4R (0.61) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30924750 0.88 TFPI (0.60) VIPR1TFPINPY2RNPY4RNPY5R
SCHEMBL30792531 0.87 VIPR1 (0.59) VIPR1TFPIVIPR2NPY2RNPY4R
SCHEMBL30924757 0.87 NPY4R (0.58) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30924735 0.87 TFPI (0.59) VIPR1TFPINPY2RNPY4RNPY5R
SCHEMBL30827587 0.87 VIPR1 (0.57) VIPR1TFPIVIPR2NPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 — — US disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 — — US disclosed
CN-116601290-A Human chimeric antigen receptor neutrophils, compositions, kits and methods of use 普渡研究基金会 2023-08-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 VIPR1 1295/4885TFPI 1593/4885VIPR2 2314/4885
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 VIPR1 1295/4885TFPI 1593/4885VIPR2 2314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback