SCHEMBL30567772

CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)C(C)C

nearest known ligand 0.76

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	5/20	0.74

▸	NPY2R	P49146	7/20	0.65

▸	NPY4R	P50391	7/20	0.65

▸	NPY5R	Q15761	7/20	0.65

▸	NPY1R	P25929	5/20	0.65

▸	CRHR1	P34998	1/20	0.65

▸	CRHR2	Q13324	1/20	0.65

▸	HCRTR1	O43613	1/20	0.64

▸	HCRTR2	O43614	1/20	0.64

▸	F2	P00734	1/20	0.62

▸	CCKBR	P32239	2/20	0.61

▸	GLP1R	P43220	2/20	0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30495668	0.94	CALCR (0.74)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL31182878	0.94	CALCR (0.70)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL31656508	0.94	CALCR (0.78)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL31182792	0.94	CALCR (0.76)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30658358	0.93	CALCR (0.77)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL31000913	0.93	CALCR (0.66)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30432502	0.93	NPY2R (0.67)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30906477	0.93	CALCR (0.67)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30432109	0.93	CALCR (0.69)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30304511	0.92	CALCR (0.69)	CALCRNPY2RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240277841-A2	HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE	NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT	2024-08-22	—	—	US	disclosed
US-20240024473-A1	HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE	PURDUE RESEARCH FOUNDATION (US)	2024-01-25	—	—	US	disclosed
CN-116601290-A	Human chimeric antigen receptor neutrophils, compositions, kits and methods of use	普渡研究基金会	2023-08-15	—	—	CN	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20240277841-A2	HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE	PBK, KIT, MYD88	CALCR 889/4885NPY2R 3831/4885NPY4R 3873/4885
US-20240024473-A1	HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE	PBK, KIT, MYD88	CALCR 889/4885NPY2R 3831/4885NPY4R 3873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.