Sugi Predict

Sugi Predict / Compounds / SCHEMBL30567784

SCHEMBL30567784

SCHEMBL30567784

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nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 8/20 0.61
▸ NPY4R P50391 8/20 0.61
▸ NPY5R Q15761 8/20 0.61
▸ NPY1R P25929 6/20 0.61
▸ CXCR4 P61073 2/20 0.58
▸ CALCR P30988 7/20 0.58
▸ EP300 Q09472 1/20 0.57
▸ HIF1A Q16665 1/20 0.57
▸ MAPK8 P45983 1/20 0.55
▸ MAPK9 P45984 1/20 0.55
▸ MAPK10 P53779 1/20 0.55
▸ RAMP3 O60896 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29827221 0.94 NPY2R (0.59) NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL30658199 0.93 NPY2R (0.63) NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL30429234 0.92 EP300 (0.62) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31507665 0.92 CALCR (0.63) NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL31683337 0.91 NPY2R (0.61) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30607453 0.91 NPY2R (0.62) NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL30435678 0.90 NPY2R (0.64) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30726569 0.90 RAMP3 (0.63) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30495607 0.90 NPY2R (0.64) NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL30567767 0.89 NPY2R (0.63) NPY2RNPY4RNPY5RNPY1RCXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 — — US disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 — — US disclosed
CN-116601290-A Human chimeric antigen receptor neutrophils, compositions, kits and methods of use 普渡研究基金会 2023-08-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 NPY2R 3831/4885NPY4R 3873/4885NPY5R 3302/4885
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 NPY2R 3831/4885NPY4R 3873/4885NPY5R 3302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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