Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 5/20 | 0.49 |
| ▸ | FNTA | P49354 | 3/20 | 0.48 |
| ▸ | FNTB | P49356 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21381763 | 1.00 | ESR2 (0.50) | ESR2STSFNTAFNTBMEN1 | |
| SCHEMBL654136 | 0.93 | ESR2 (0.48) | ESR2STSFNTAFNTBMEN1 | |
| SCHEMBL654135 | 0.93 | ESR2 (0.48) | ESR2STSFNTAFNTBMEN1 | |
| SCHEMBL8223384 | 0.83 | ESR2 (0.60) | ESR2STSMEN1KMT2ADDB1 | |
| SCHEMBL21381774 | 0.81 | DPP4 (0.42) | MEN1KMT2ANAMPT | |
| SCHEMBL653757 | 0.79 | DDB1 (0.42) | ESR2STSFNTAFNTBMEN1 | |
| SCHEMBL653159 | 0.79 | DDB1 (0.42) | ESR2STSFNTAFNTBMEN1 | |
| SCHEMBL24187342 | 0.79 | MEN1 (0.48) | STSFNTAFNTBMEN1KMT2A | |
| SCHEMBL21381843 | 0.79 | STS (0.53) | STSFNTAFNTBMEN1KMT2A | |
| SCHEMBL4993502 | 0.79 | ESR2 (0.48) | ESR2STSFNTAFNTBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |