Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 18/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23828233 | 0.88 | CFTR (0.52) | CFTRHTR2A | |
| SCHEMBL23828295 | 0.88 | CFTR (0.52) | CFTRHTR2A | |
| SCHEMBL23828291 | 0.81 | CFTR (0.79) | CFTR | |
| SCHEMBL23828237 | 0.79 | CFTR (0.52) | CFTRHTR2A | |
| SCHEMBL23828317 | 0.74 | CFTR (0.64) | CFTRHTR2A | |
| SCHEMBL23828202 | 0.71 | CFTR (0.75) | CFTR | |
| SCHEMBL23828258 | 0.70 | CFTR (1.00) | CFTR | |
| SCHEMBL21617988 | 0.69 | CFTR (0.70) | CFTR | |
| SCHEMBL31020987 | 0.69 | CFTR (0.70) | CFTR | |
| SCHEMBL23828264 | 0.67 | CFTR (1.00) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820867-B1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS | FONDAZIONE ST ITALIANO TECNOLOGIA (IT) | 2023-09-13 | — | — | EP | claimed |