SCHEMBL305707

SCHEMBL305707

N[C@@H](CCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 1.00
FOLH1 Q04609 2/20 0.61
MEN1 O00255 1/20 0.60
ABL1 P00519 1/20 0.60
LMNA P02545 1/20 0.60
PKM P14618 1/20 0.60
IDE P14735 1/20 0.60
MAPK1 P28482 1/20 0.60
KMT2A Q03164 1/20 0.60
RIN1 Q13671 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
CA12 O43570 4/20 0.58
CA1 P00915 4/20 0.58
CA2 P00918 4/20 0.58
CA9 Q16790 4/20 0.58
CAPN1 P07384 2/20 0.57
PLCD1 P51178 1/20 0.54
ITGB1 P05556 1/20 0.52
ITGA4 P13612 1/20 0.52
FGF1 P05230 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424058 1.00 TDP1 (1.00) TDP1FOLH1MEN1ABL1LMNA
SCHEMBL17776290 1.00 TDP1 (1.00) TDP1FOLH1MEN1ABL1LMNA
SCHEMBL13510665 1.00 TDP1 (1.00) TDP1FOLH1MEN1ABL1LMNA
SCHEMBL31429755 1.00 TDP1 (1.00) TDP1FOLH1MEN1ABL1LMNA
SCHEMBL564538 1.00 TDP1 (1.00) TDP1FOLH1MEN1ABL1LMNA
SCHEMBL305706 1.00 TDP1 (1.00) TDP1FOLH1MEN1ABL1LMNA
SCHEMBL10171640 1.00 TDP1 (1.00) TDP1FOLH1MEN1ABL1LMNA
Hydrazine SCHEMBL1270033 0.99 TDP1 (0.98) TDP1FOLH1MEN1ABL1LMNA
SCHEMBL9168421 0.99 TDP1 (0.98) TDP1FOLH1MEN1ABL1LMNA
SCHEMBL565396 0.99 TDP1 (0.98) TDP1FOLH1MEN1ABL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4591 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US claimed
WO-2026107515-A1 INCRETIN HORMONE COMPOSITIONS AND METHODS USING SAME DIASOME PHARMACEUTICALS, INC. (US) 2026-05-21 WO claimed
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL DIASOME PHARMACEUTICALS INC (US) 2026-05-07 US claimed
WO-2026087688-A1 TRACER COMPOUNDS FOR WHOLE CELL LABELLING Charité - Universitätsmedizin Berlin Körperschaft des öffentlichen Rechts (DE) 2026-04-30 WO claimed
EP-4733763-A1 TRACER COMPOUNDS FOR WHOLE CELL LABELLING Charité - Universitätsmedizin Berlin Körperschaft des öffentlichen Rechts (DE) 2026-04-29 EP claimed
EP-4704902-A1 A COMBINATION THERAPY FOR CANCER TREATMENT Purdue Research Foundation (US) 2026-03-11 EP claimed
US-20250367099-A1 UROLITHIN COMBINATIONS DAMICO DAVIDE (CH) 2025-12-04 US claimed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US claimed
CN-120064656-A Urine marker for ischemic acute kidney injury and screening method and application thereof 深圳市人民医院 2025-05-30 CN claimed
US-12203936-B2 Detection of glutathionylated proteins UNIVERSITEIT MAASTRICHT (NL) 2025-01-21 US claimed
EP-0721347-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS Beiersdorf Aktiengesellschaft (DE) 1996-07-17 EP claimed
WO-1995015983-A1 PROCESS FOR IMMOBILISING BIOMOLECULES AND AFFINITY LIGANDS ON POLYMER CARRIERS GLUESENKAMP KARL HEINZ (DE) 1995-06-15 WO claimed
EP-0379949-B1 Method for the determination of HIV antibodies BOEHRINGER MANNHEIM GMBH (DE) 1995-03-29 EP claimed
WO-1995005852-A1 AGENT AGAINST SENSITIVE, HYPERREACTIVE AND HYPOACTIVE STATES OF THE SKIN, FORMS OF ACNE, ATOPIC DERMATITIDES, PSORIASIS, PRURIGO, PHOTODERMATOSES, ICHTHYOSIS AND VIRAL INFECTIONS BEIERSDORF AG (DE) 1995-03-02 WO claimed
WO-1995002418-A1 RADIONUCLIDE METAL CHELATES FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS NEORX CORPORATION (US) 1995-01-26 WO claimed
US-5108921-A Contacting living cell membrane with complex of biotin and derivatives and biologically functional molecules; modifying cell function PURDUE RESEARCH FOUNDATION (US) 1992-04-28 US claimed
WO-1991016116-A1 IMMUNOSELECTION DEVICE AND METHOD CELLPRO INCORPORATED (US) 1991-10-31 WO claimed
US-5001049-A Method for determination of HIV specific antibodies BOEHRINGER MANNHEIM GMBH (DE) 1991-03-19 US claimed
EP-0379949-A2 Method for the determination of HIV antibodies Roche Diagnostics GmbH (DE) 1990-08-01 EP claimed
EP-0284549-A2 Magnetic fluid compositions Silica Gel Ges.mbH Absorptionstechnik, Apparatebau (DE) 1988-09-28 EP claimed