SCHEMBL30574124

SCHEMBL30574124

COc1ccc(Nc2nc(Br)cn3ccnc23)cc1OC

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SYK P43405 20/20 0.64
CD63 P08962 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2897712 1.00 SYK (0.64) SYKCD63
SCHEMBL13746497 0.91 SYK (0.54) SYKCD63
SCHEMBL12016085 0.87 SYK (0.52) SYKCD63
SCHEMBL2894129 0.87 SYK (0.49) SYKCD63
SCHEMBL15250791 0.86 SYK (0.64) SYKCD63
SCHEMBL15551557 0.85 SYK (0.49) SYKCD63
SCHEMBL15550736 0.83 SYK (0.65) SYKCD63
SCHEMBL2895418 0.82 SYK (0.75) SYKCD63
SCHEMBL2481025 0.82 SYK (0.81) SYKCD63
SCHEMBL2483250 0.81 SYK (0.77) SYKCD63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4493188-A2 SPLEEN TYROSINE KINASE INHIBITOR, COMPOSITION, AND METHODS OF USE Purdue Research Foundation (US) 2025-01-22 EP disclosed
CN-119300822-A Spleen tyrosine kinase inhibitors, compositions, and methods of use 普渡研究基金会 2025-01-10 CN disclosed
WO-2023178094-A2 SPLEEN TYROSINE KINASE INHIBITOR, COMPOSITION, AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2023-09-21 WO disclosed