SCHEMBL30574341

SCHEMBL30574341

Fc1ccc(OCc2ccc(-c3nnc(C(F)F)o3)cn2)cc1F

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 19/20 0.49
HDAC1 Q13547 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26125462 1.00 HDAC6 (0.49) HDAC6HDAC1
SCHEMBL26530401 0.91 HDAC6 (0.42) HDAC6HDAC1
SCHEMBL26529785 0.88 HDAC6 (0.46) HDAC6HDAC1
SCHEMBL26529863 0.88 HDAC6 (0.44) HDAC6HDAC1
SCHEMBL30574361 0.87 HDAC6 (0.52) HDAC6
SCHEMBL26124131 0.87 HDAC6 (0.52) HDAC6
SCHEMBL26529762 0.86 HDAC6 (0.52) HDAC6
SCHEMBL26128684 0.86 HDAC6 (0.62) HDAC6HDAC1
SCHEMBL26528747 0.85 HDAC6 (0.49) HDAC6HDAC1
SCHEMBL34463618 0.84 HDAC6 (0.46) HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119451678-A Inhibition of histone deacetylase 6 (HDAC 6) 艾科尼佐治疗股份有限公司 2025-02-14 CN claimed
EP-4504191-A1 INHIBITING HISTONE DEACETYLASE 6 (HDAC6) Eikonizo Therapeutics, Inc. (US) 2025-02-12 EP claimed
WO-2023196605-A1 INHIBITING HISTONE DEACETYLASE 6 (HDAC6) EIKONIZO THERAPEUTICS, INC. (US) 2023-10-12 WO claimed
US-20250250263-A1 INHIBITING HISTONE DEACETYLASE 6 (HDAC6) EIKONIZO THERAPEUTICS, INC. (US) 2025-08-07 US disclosed
CN-119451678-A Inhibition of histone deacetylase 6 (HDAC 6) 艾科尼佐治疗股份有限公司 2025-02-14 CN disclosed
EP-4504191-A1 INHIBITING HISTONE DEACETYLASE 6 (HDAC6) Eikonizo Therapeutics, Inc. (US) 2025-02-12 EP disclosed
EP-4504190-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF Eikonizo Therapeutics, Inc. (US) 2025-02-12 EP disclosed
CN-119212707-A Oxadiazole HDAC6 inhibitors and uses thereof 艾科尼佐治疗股份有限公司 2024-12-27 CN disclosed
WO-2023196601-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF EIKONIZO THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed
WO-2023196605-A1 INHIBITING HISTONE DEACETYLASE 6 (HDAC6) EIKONIZO THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250250263-A1 INHIBITING HISTONE DEACETYLASE 6 (HDAC6) HDAC6, HDAC1, HDAC9 HDAC6 1/4885HDAC1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.