SCHEMBL30575424

SCHEMBL30575424

Cc1cc(OCCOCCP(=O)(O)O)ccc1CCc1cnc2c(N)nc3cc(CCC(=O)O)ccc3c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29886757 1.00 TLR7 (1.00) TLR7
SCHEMBL161530 1.00 TLR7 (1.00) TLR7
SCHEMBL255136 1.00 TLR7 (1.00) TLR7
SCHEMBL1527485 1.00 TLR7 (1.00) TLR7
SCHEMBL17874560 0.95 TLR7 (0.90) TLR7
SCHEMBL12290514 0.95 TLR7 (0.90) TLR7
SCHEMBL16284901 0.95 TLR7 (0.90) TLR7
SCHEMBL173879 0.94 TLR7 (1.00) TLR7
SCHEMBL30575433 0.94 TLR7 (1.00) TLR7
SCHEMBL12841040 0.93 TLR7 (0.88) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240009215-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING SOLID TUMORS BY INTRATUMORAL ADMINISTRATION NOVARTIS AG (CH) 2024-01-11 US disclosed
US-11752162-B2 Compounds and compositions for treating solid tumors by intratumoral administration NOVARTIS AG (CH) 2023-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11752162-B2 Compounds and compositions for treating solid tumors by intratumoral administration TLR7, TLR9, TLR3 TLR7 1/4885
US-20240009215-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING SOLID TUMORS BY INTRATUMORAL ADMINISTRATION TLR7, TLR9, TLR3 TLR7 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.