SCHEMBL30575432

SCHEMBL30575432

Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(OCCCCP(=O)(O)O)cc3C)cc12

nearest known ligand 0.98

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173264 1.00 TLR7 (0.98) TLR7
SCHEMBL1527631 0.99 TLR7 (1.00) TLR7
SCHEMBL30575428 0.99 TLR7 (1.00) TLR7
SCHEMBL30575443 0.99 TLR7 (1.00) TLR7
SCHEMBL170115 0.99 TLR7 (1.00) TLR7
SCHEMBL173521 0.97 TLR7 (1.00) TLR7
SCHEMBL30575438 0.97 TLR7 (1.00) TLR7
SCHEMBL1527557 0.96 TLR7 (1.00) TLR7
SCHEMBL30575435 0.96 TLR7 (1.00) TLR7
SCHEMBL17874564 0.95 TLR7 (0.89) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240009215-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING SOLID TUMORS BY INTRATUMORAL ADMINISTRATION NOVARTIS AG (CH) 2024-01-11 US disclosed
US-11752162-B2 Compounds and compositions for treating solid tumors by intratumoral administration NOVARTIS AG (CH) 2023-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11752162-B2 Compounds and compositions for treating solid tumors by intratumoral administration TLR7, TLR9, TLR3 TLR7 1/4885
US-20240009215-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING SOLID TUMORS BY INTRATUMORAL ADMINISTRATION TLR7, TLR9, TLR3 TLR7 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.