SCHEMBL30576395

SCHEMBL30576395

O=C=Nc1ccccc1P(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.44
TDP1 Q9NUW8 2/20 0.41
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
DRD1 P21728 2/20 0.34
TRPA1 O75762 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31544485 0.79 CYP3A4 (0.35) CYP3A4TDP1ALDH1A1HPGD
SCHEMBL20903826 0.78 CYP3A4 (0.46) CYP3A4TDP1ESR1ESR2DRD1
Benzene SCHEMBL28766229 0.76 CYP3A4 (0.61) CYP3A4TDP1DRD1TRPA1KDM4E
SCHEMBL5172777 0.74 CYP3A4 (0.46) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL15431 0.73 CYP3A4 (0.64) CYP3A4TDP1DRD1TRPA1KDM4E
SCHEMBL29395383 0.73 CYP3A4 (0.64) CYP3A4TDP1DRD1TRPA1KDM4E
SCHEMBL9791083 0.72 CYP3A4 (0.50) CYP3A4TDP1ESR1ESR2TRPA1
Fluoride SCHEMBL28813057 0.71 CYP3A4 (0.61) CYP3A4TDP1DRD1TRPA1KDM4E
Water SCHEMBL28526910 0.71 CYP3A4 (0.61) CYP3A4TDP1DRD1TRPA1KDM4E
SCHEMBL30244709 0.71 CYP3A4 (0.61) CYP3A4TDP1DRD1TRPA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957659-B Polyoxadiazole and preparation method and application thereof 深圳大学 2023-09-22 CN disclosed