Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 5/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 10/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.48 |
| ▸ | DPP4 | P27487 | 5/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26661822 | 1.00 | KCNQ2 (0.60) | KCNQ2DPP9DPP8DPP4DPP7 | |
| SCHEMBL38659467 | 0.94 | KCNQ2 (0.56) | KCNQ2DPP9DPP8DPP4DPP7 | |
| SCHEMBL38659319 | 0.93 | KCNQ2 (0.55) | KCNQ2DPP9DPP8DPP4DPP7 | |
| SCHEMBL38660352 | 0.90 | KCNQ2 (0.50) | KCNQ2DPP9DPP8DPP4DPP7 | |
| SCHEMBL30487433 | 0.90 | KCNQ2 (0.53) | KCNQ2DPP9DPP8DPP4DPP7 | |
| SCHEMBL31020139 | 0.89 | KCNQ2 (0.52) | KCNQ2DPP9DPP8DPP4DPP7 | |
| SCHEMBL38660003 | 0.89 | KCNQ2 (0.48) | KCNQ2DPP9DPP8DPP4DPP7 | |
| SCHEMBL38658821 | 0.89 | KCNQ2 (0.48) | KCNQ2DPP9DPP8DPP4DPP7 | |
| SCHEMBL31519813 | 0.85 | KCNQ2 (0.45) | KCNQ2DPP9DPP8DPP4DPP7 | |
| SCHEMBL31020030 | 0.84 | KCNQ2 (0.44) | KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026102345-A1 | METHODS OF ADMINISTERING THE VOLTAGE-GATED POTASSIUM CHANNEL OPENER AZETUKALNER | XENON PHARMACEUTICALS INC. (CA) | 2026-05-15 | — | — | WO | disclosed |
| WO-2025179128-A1 | AZETUKALNER FOR USE IN THE TREATMENT OF DEPRESSION, ANHEDONIA OR A SEIZURE DISORDER SUCH AS EPILEPSY IN PEDIATRIC SUBJECTS | XENON PHARMACEUTICALS INC. (CA) | 2025-08-28 | — | — | WO | disclosed |
| CN-116847843-A | Voltage-gated potassium channel openers for treating anorgasmia | 泽农医药公司 | 2023-10-03 | — | — | CN | disclosed |