Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30577554 | 0.92 | GRM2 (0.33) | KLKB1KDM4EHRH3HRH2HRH1 | |
| SCHEMBL30540453 | 0.90 | KLKB1 (0.39) | KLKB1KDM4EHRH3L3MBTL1LMNA | |
| SCHEMBL30540580 | 0.88 | KLKB1 (0.37) | KLKB1KDM4EHRH3L3MBTL1LMNA | |
| SCHEMBL31115338 | 0.83 | KDM4E (0.36) | KLKB1KDM4EHRH3L3MBTL1LMNA | |
| SCHEMBL30540610 | 0.83 | KDM4E (0.36) | KLKB1KDM4EHRH3L3MBTL1LMNA | |
| SCHEMBL30540679 | 0.81 | KLKB1 (0.38) | KLKB1KDM4EHRH3L3MBTL1LMNA | |
| SCHEMBL31115364 | 0.80 | KLKB1 (0.33) | KLKB1KDM4EHRH3L3MBTL1LMNA | |
| SCHEMBL31115342 | 0.80 | GRM2 (0.35) | KLKB1KDM4EHRH3L3MBTL1LMNA | |
| SCHEMBL30540464 | 0.80 | KLKB1 (0.33) | KLKB1KDM4EHRH3L3MBTL1LMNA | |
| SCHEMBL30540583 | 0.80 | GRM2 (0.35) | KLKB1KDM4EHRH3L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151641-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |