Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.59 |
| ▸ | CDK5 | Q00535 | 11/20 | 0.51 |
| ▸ | CDK2 | P24941 | 10/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 10/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 9/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20541883 | 1.00 | CDK1 (0.59) | CDK1CDK5CDK2CDK5R1CCNA2 | |
| SCHEMBL17628610 | 0.81 | CDK1 (0.79) | CDK1CDK5CDK2CDK5R1CCNA2 | |
| SCHEMBL20542017 | 0.80 | AHR (0.45) | CDK1CDK5CDK2CDK5R1CCNA2 | |
| SCHEMBL30579387 | 0.80 | AHR (0.45) | CDK1CDK5CDK2CDK5R1CCNA2 | |
| SCHEMBL20541790 | 0.78 | CDK1 (0.61) | CDK1CDK5CDK2CDK5R1CCNA2 | |
| SCHEMBL2318905 | 0.75 | CDK1 (0.62) | CDK1CDK5CDK2CDK5R1CCNA2 | |
| SCHEMBL20558018 | 0.75 | CDK1 (0.54) | CDK1CDK5CDK2CDK5R1CCNA2 | |
| SCHEMBL1400442 | 0.74 | CDK1 (1.00) | CDK1CDK5CDK2DYRK1ACYP2D6 | |
| SCHEMBL20541955 | 0.74 | CDK1 (0.58) | CDK1CDK5CDK2CDK5R1CCNA2 | |
| SCHEMBL6817833 | 0.74 | CDK1 (0.63) | CDK1CDK5CDK2CDK5R1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831600-B | Indole AHR inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2023-10-17 | — | — | CN | disclosed |