Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30580359 | 1.00 | TSHR (0.47) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL10171869 | 0.87 | TSHR (0.41) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL30210778 | 0.80 | TSHR (0.52) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL6138331 | 0.80 | TSHR (0.52) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL22110584 | 0.77 | TSHR (0.58) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL599898 | 0.77 | TSHR (0.48) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL10171946 | 0.77 | TSHR (0.48) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL18631044 | 0.77 | TSHR (0.52) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL21297456 | 0.77 | TSHR (0.52) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL18631046 | 0.77 | TSHR (0.52) | TSHRTAAR1LMNABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242204-A1 | CD73 INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2023-09-13 | — | — | EP | disclosed |