Phenanthroline

Phenanthroline

SCHEMBL3058164

[O-][Cl+3]([O-])([O-])[O-].[O-][Cl+3]([O-])([O-])[O-].[Os+2].c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.76
CCR8 P51685 5/20 0.76
LMNA P02545 4/20 0.76
CCR5 P51681 3/20 0.76
KDM4E B2RXH2 3/20 0.76
MAPT P10636 3/20 0.76
MMP2 P08253 2/20 0.76
TSHR P16473 2/20 0.76
HTT P42858 2/20 0.76
SMN1; SMN2 Q16637 2/20 0.76
TDP1 Q9NUW8 2/20 0.76
GMNN O75496 1/20 0.76
TP53 P04637 1/20 0.76
HSP90AA1 P07900 1/20 0.76
CYP3A4 P08684 1/20 0.76
CYP2D6 P10635 1/20 0.76
MMP9 P14780 1/20 0.76
ALOX15 P16050 1/20 0.76
NFKB1 P19838 1/20 0.76
MMP8 P22894 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenanthroline SCHEMBL2459148 0.95 CCR1 (0.76) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL3126612 0.95 CCR1 (0.76) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL9640537 0.95 CCR1 (0.76) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL497012 0.95 CCR1 (0.76) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL1928813 0.95 CCR1 (0.76) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL30112674 0.95 CCR1 (0.76) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL30613745 0.90 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL8994184 0.90 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL8312 0.87 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL29354015 0.87 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10031120-B2 Devices and methods for detecting an explosive substance TRACE EYE-D, LLC (US) 2018-07-24 US claimed
US-20180113106-A1 DEVICES AND METHODS FOR DETECTING AN EXPLOSIVE SUBSTANCE GEORGE L. SOUTHWORTH REVOCABLE TRUST 2018-04-26 US claimed
EP-2126551-B1 ANALYSIS OF FUNCTIONAL FLUIDS LUBRIZOL CORP (US) 2016-08-10 EP claimed
US-20100268169-A1 AUTOINJECTOR WITH DESHIELDER COMPRISING TAMPER EVIDENCE MEANS BECTON DICKINSON FRANCE S.A.S. (FR) 2010-10-21 US claimed
US-20080206874-A1 Analysis of Functional Fluids THE LUBRIZOL CORPORATION (US) 2008-08-28 US claimed
US-20080206879-A1 Analysis of Functional Fluids Using a Redox Indicator THE LUBRIZOL CORPORATION (US) 2008-08-28 US claimed
US-10746717-B2 Devices and methods for detecting an explosive substance TRACE EYE-D, LLC (US) 2020-08-18 US disclosed
US-20180299421-A1 DEVICES AND METHODS FOR DETECTING AN EXPLOSIVE SUBSTANCE GEORGE L. SOUTHWORTH REVOCABLE TRUST 2018-10-18 US disclosed
US-10031120-B2 Devices and methods for detecting an explosive substance TRACE EYE-D, LLC (US) 2018-07-24 US disclosed
US-10024834-B2 Devices and methods for detecting an explosive substance TRACE EYE-D, LLC (US) 2018-07-17 US disclosed
US-20180113107-A1 DEVICES AND METHODS FOR DETECTING AN EXPLOSIVE SUBSTANCE GEORGE L. SOUTHWORTH REVOCABLE TRUST 2018-04-26 US disclosed
US-20180113106-A1 DEVICES AND METHODS FOR DETECTING AN EXPLOSIVE SUBSTANCE GEORGE L. SOUTHWORTH REVOCABLE TRUST 2018-04-26 US disclosed
EP-2126551-B1 ANALYSIS OF FUNCTIONAL FLUIDS LUBRIZOL CORP (US) 2016-08-10 EP disclosed
US-20080206874-A1 Analysis of Functional Fluids THE LUBRIZOL CORPORATION (US) 2008-08-28 US disclosed
US-20080206879-A1 Analysis of Functional Fluids Using a Redox Indicator THE LUBRIZOL CORPORATION (US) 2008-08-28 US disclosed