SCHEMBL30583178

SCHEMBL30583178

CCCCn1c(Cc2cc(OC)ccc2OC)nc2c(N)nc(F)nc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 14/20 1.00
HSP90AB1 P08238 14/20 1.00
ERBB2 P04626 10/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4323418 1.00 HSP90AA1 (1.00) HSP90AA1HSP90AB1ERBB2
SCHEMBL4309310 0.97 HSP90AA1 (0.94) HSP90AA1HSP90AB1ERBB2
SCHEMBL1966143 0.91 HSP90AB1 (0.82) HSP90AA1HSP90AB1ERBB2
SCHEMBL1963448 0.89 HSP90AB1 (0.81) HSP90AA1HSP90AB1ERBB2
SCHEMBL30583135 0.89 HSP90AA1 (1.00) HSP90AA1HSP90AB1ERBB2
SCHEMBL1964321 0.89 HSP90AA1 (1.00) HSP90AA1HSP90AB1ERBB2
SCHEMBL30583202 0.85 HSP90AA1 (1.00) HSP90AA1HSP90AB1ERBB2
SCHEMBL1964201 0.85 HSP90AA1 (1.00) HSP90AA1HSP90AB1ERBB2
SCHEMBL1963778 0.85 HSP90AB1 (0.73) HSP90AA1HSP90AB1ERBB2
SCHEMBL1966393 0.82 HSP90AB1 (0.70) HSP90AA1HSP90AB1ERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed