Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 16/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26662590 | 1.00 | PIK3CA (0.54) | PIK3CAPIK3CBPIK3CDPIK3CGCYP1A1 | |
| SCHEMBL26662582 | 1.00 | PIK3CA (0.54) | PIK3CAPIK3CBPIK3CDPIK3CGCYP1A1 | |
| SCHEMBL30742239 | 0.86 | PIK3CA (0.44) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL27129685 | 0.86 | PIK3CA (0.44) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL26871116 | 0.86 | PIK3CA (0.44) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL26662608 | 0.85 | PIK3CA (0.40) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL26662604 | 0.85 | PIK3CA (0.40) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL30584382 | 0.85 | PIK3CA (0.40) | PIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL30584279 | 0.85 | PIK3CA (0.57) | PIK3CAPIK3CBPIK3CDPIK3CGCYP1A1 | |
| SCHEMBL26662600 | 0.85 | PIK3CA (0.57) | PIK3CAPIK3CBPIK3CDPIK3CGCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514784-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-03-05 | — | — | EP | disclosed |
| CN-119301106-A | Allosteric benzopyrone inhibitors of phosphoinositide 3-kinase (PI 3K) for the treatment of disease | 佩特拉制药公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2023212693-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2023-11-02 | — | — | WO | disclosed |