Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26662560 | 1.00 | PIK3CA (0.45) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL26662556 | 1.00 | PIK3CA (0.45) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL26662502 | 0.94 | PIK3CA (0.46) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL26662498 | 0.94 | PIK3CA (0.46) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL30584280 | 0.94 | PIK3CA (0.46) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL27129685 | 0.94 | PIK3CA (0.44) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL30742239 | 0.94 | PIK3CA (0.44) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL26871116 | 0.94 | PIK3CA (0.44) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL27021987 | 0.92 | PIK3CA (0.45) | PIK3CAAKT1AKT2AKT3PIK3CB | |
| SCHEMBL30742080 | 0.92 | PIK3CA (0.44) | PIK3CAAKT1AKT2AKT3PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514784-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-03-05 | — | — | EP | disclosed |
| CN-119301106-A | Allosteric benzopyrone inhibitors of phosphoinositide 3-kinase (PI 3K) for the treatment of disease | 佩特拉制药公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2023212693-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2023-11-02 | — | — | WO | disclosed |