SCHEMBL30584780

SCHEMBL30584780

CC(C)(C)OC(=O)N1CCC[C@H](CN2CCC(CNC(=O)C3CCN(c4nc(-c5ccc(Cl)cc5)no4)CC3)C2)C1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ HDAC4 P56524 2/20 0.44
▸ HDAC6 Q9UBN7 2/20 0.44
▸ MAPT P10636 5/20 0.43
▸ LMNA P02545 2/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ ACKR3 P25106 1/20 0.42
▸ POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584760 1.00 MEN1 (0.44) MEN1KMT2AHDAC4HDAC6MAPT
SCHEMBL30584752 1.00 MEN1 (0.44) MEN1KMT2AHDAC4HDAC6MAPT
SCHEMBL30584961 0.92 MEN1 (0.54) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584852 0.92 MEN1 (0.54) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584709 0.92 MEN1 (0.54) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584978 0.92 MEN1 (0.54) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584913 0.92 MEN1 (0.54) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL25438967 0.91 SMN1; SMN2 (0.49) MEN1KMT2AHDAC4HDAC6MAPT
SCHEMBL30584737 0.91 SMN1; SMN2 (0.49) MEN1KMT2AHDAC4HDAC6MAPT
SCHEMBL30584773 0.91 SMN1; SMN2 (0.49) MEN1KMT2AHDAC4HDAC6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885HDAC4 2103/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885HDAC4 2103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback