Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25403067 | 0.86 | MAPT (0.61) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL31546398 | 0.82 | MAPT (0.75) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL31546316 | 0.82 | MAPT (0.76) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL31546357 | 0.82 | MAPT (0.63) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL31546320 | 0.82 | MAPT (0.75) | MAPTLMNANPC1HTTALDH1A1 | |
| SCHEMBL30418761 | 0.81 | SPHK2 (0.59) | MAPTLMNANPC1HTTHSP90AA1 | |
| SCHEMBL25400988 | 0.81 | MEN1 (0.67) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL25435527 | 0.80 | MEN1 (0.68) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL25402791 | 0.80 | MEN1 (0.59) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL30584744 | 0.80 | MEN1 (0.66) | MAPTLMNANPC1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463452-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023177700-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2023-09-21 | — | — | WO | disclosed |