SCHEMBL30584856

SCHEMBL30584856

O=C(NCC1CCN(CC2CCCN(C(=O)O)C2)C1)C1CCN(c2nc(-c3ccc(Cl)cc3)no2)CC1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.46
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ LMNA P02545 3/20 0.44
▸ GAA P10253 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ HSD11B1 P28845 1/20 0.40
▸ POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30585013 1.00 MAPT (0.46) MAPTMEN1KMT2ALMNAGAA
SCHEMBL25402463 0.91 MEN1 (0.48) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL31546363 0.91 MEN1 (0.48) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL25402468 0.91 MEN1 (0.48) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL25435289 0.91 MEN1 (0.48) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL25436110 0.91 MEN1 (0.48) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL25435085 0.91 MEN1 (0.48) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL25439278 0.90 MAPT (0.52) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL25439279 0.90 MAPT (0.52) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL25439629 0.90 MAPT (0.52) MAPTMEN1KMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed
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