Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584968 | 1.00 | MAPT (0.58) | MAPTLMNAHTTNPC1HDAC4 | |
| SCHEMBL25433114 | 0.85 | MAPT (0.75) | MAPTLMNAHTTNPC1HDAC4 | |
| SCHEMBL18624608 | 0.83 | MAPT (0.62) | MAPTLMNAHTTNPC1HDAC4 | |
| SCHEMBL30584728 | 0.82 | MAPT (0.59) | MAPTLMNAHTTNPC1HDAC4 | |
| SCHEMBL17115031 | 0.82 | MAPT (0.58) | MAPTLMNAHTTNPC1HDAC4 | |
| SCHEMBL17100788 | 0.82 | MAPT (0.57) | MAPTLMNAHTTNPC1HDAC4 | |
| SCHEMBL30584762 | 0.82 | MAPT (0.58) | MAPTLMNAHTTNPC1HDAC4 | |
| SCHEMBL25434428 | 0.81 | MAPT (0.55) | MAPTLMNAHTTNPC1HDAC4 | |
| SCHEMBL18603147 | 0.80 | HDAC4 (0.63) | MAPTLMNAHTTNPC1HDAC4 | |
| SCHEMBL17115033 | 0.79 | HDAC4 (0.54) | MAPTLMNAHTTNPC1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463452-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023177700-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2023-09-21 | — | — | WO | disclosed |