⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26247580 | 1.00 | — | — | |
| SCHEMBL9188293 | 1.00 | — | — | |
| SCHEMBL894866 | 1.00 | — | — | |
| SCHEMBL897672 | 1.00 | — | — | |
| SCHEMBL26247587 | 1.00 | — | — | |
| SCHEMBL26247584 | 1.00 | — | — | |
| SCHEMBL8609056 | 0.99 | — | — | |
| SCHEMBL13743071 | 0.94 | — | — | |
| SCHEMBL11667006 | 0.88 | — | — | |
| SCHEMBL1492018 | 0.88 | KCNA5 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867510-A | Treatment of liver disease with mitochondrial glycerol-3-phosphate acyltransferase (GPAM) inhibitors | 雷杰纳荣制药公司 | 2023-10-10 | — | — | CN | disclosed |