Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 8/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26530966 | 0.92 | LCK (0.42) | ATRLCKMAPKAPK2RORC | |
| SCHEMBL30587248 | 0.92 | LCK (0.42) | ATRLCKMAPKAPK2RORC | |
| SCHEMBL26116037 | 0.85 | CSNK2A2 (0.46) | CSNK2A2KDRCSNK2BCSNK2A1CCNC | |
| SCHEMBL30587256 | 0.85 | CSNK2A2 (0.46) | CSNK2A2KDRCSNK2BCSNK2A1CCNC | |
| SCHEMBL30587290 | 0.79 | LCK (0.34) | ATRLCKMAPKAPK2TP53NPC1 | |
| SCHEMBL26115151 | 0.77 | HDAC3 (0.36) | TP53 | |
| SCHEMBL30587276 | 0.74 | DAO (0.49) | CCNCCDK8TP53NPC1PKM | |
| SCHEMBL26116056 | 0.74 | DAO (0.49) | CCNCCDK8TP53NPC1PKM | |
| SCHEMBL30587238 | 0.71 | ATR (0.51) | ATRLCK | |
| SCHEMBL26118724 | 0.71 | ATR (0.51) | ATRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499233-A1 | KRAS INHIBITORS | Eli Lilly and Company (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023183585-A1 | KRAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-09-28 | — | — | WO | disclosed |