Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404180 | 0.82 | KMT2A (0.64) | KMT2AHRH4HRH3MEN1POLB | |
| SCHEMBL1629877 | 0.78 | TOP2A (0.60) | HRH4MAPK1ALDH1A1MAPT | |
| SCHEMBL38665457 | 0.78 | TOP2A (0.60) | HRH4MAPK1ALDH1A1MAPT | |
| SCHEMBL26116598 | 0.77 | KMT2A (1.00) | KMT2AMEN1POLBRAB9AKDM4E | |
| SCHEMBL31325815 | 0.77 | KDM4E (0.53) | KMT2AMEN1POLBMAPK1KDM4E | |
| SCHEMBL10852385 | 0.76 | KMT2A (0.49) | KMT2AMEN1POLBTP53MAPT | |
| SCHEMBL38664610 | 0.76 | KDM4E (0.49) | KMT2AMEN1MAPK1KDM4EALDH1A1 | |
| SCHEMBL404191 | 0.74 | HRH4 (1.00) | KMT2AHRH4HRH3POLBMAPK1 | |
| SCHEMBL404201 | 0.73 | HRH4 (0.76) | KMT2AHRH4HRH3POLBMAPK1 | |
| SCHEMBL10846882 | 0.73 | HCRTR1 (0.46) | KMT2AMEN1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183285-A1 | METHODS OF DIAGNOSING AND TREATING NEURODEGENERATIVE DISEASES | THE GENERAL HOSPITAL CORPORATION (US) | 2023-09-28 | — | — | WO | disclosed |