⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18366793 | 1.00 | — | — | |
| SCHEMBL30587524 | 0.97 | — | — | |
| SCHEMBL18367168 | 0.97 | — | — | |
| SCHEMBL18366861 | 0.87 | — | — | |
| SCHEMBL30092726 | 0.87 | — | — | |
| SCHEMBL30036897 | 0.85 | — | — | |
| SCHEMBL22888172 | 0.85 | — | — | |
| SCHEMBL18366944 | 0.85 | — | — | |
| SCHEMBL30587522 | 0.81 | — | — | |
| SCHEMBL18366847 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269221-B | Bicyclic lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-09-26 | — | — | CN | disclosed |