Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 10/20 | 0.61 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.54 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604579 | 1.00 | PHF8 (0.61) | PHF8KDM4CKDM2BKDM4AKDM5B | |
| SCHEMBL17693334 | 0.92 | PHF8 (0.58) | PHF8KDM4CKDM2BKDM4AKDM5B | |
| SCHEMBL17686545 | 0.92 | PHF8 (0.61) | PHF8KDM4CKDM2BKDM4AKDM5B | |
| SCHEMBL17686569 | 0.92 | PHF8 (0.57) | PHF8KDM4CKDM2BKDM4AKDM5B | |
| SCHEMBL30589240 | 0.92 | PHF8 (0.57) | PHF8KDM4CKDM2BKDM4AKDM5B | |
| SCHEMBL30589234 | 0.92 | PHF8 (0.61) | PHF8KDM4CKDM2BKDM4AKDM5B | |
| SCHEMBL17604642 | 0.89 | KDM2B (0.58) | PHF8KDM4CKDM2BKDM4AKDM5B | |
| SCHEMBL19383320 | 0.85 | PHF8 (0.73) | PHF8KDM4CKDM2BKDM4AKDM5B | |
| SCHEMBL24244156 | 0.77 | PHF8 (0.70) | PHF8KDM4CKDM2BKDM4AKDM5B | |
| SCHEMBL19383405 | 0.77 | PHF8 (0.66) | PHF8KDM4CKDM2BKDM4AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |