Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 13/20 | 0.70 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | KDM6B | O15054 | 2/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891743 | 1.00 | KDM5B (0.70) | KDM5BKDM4CKDM2BKDM6BPHF8 | |
| SCHEMBL17891725 | 0.91 | KDM5B (0.69) | KDM5BKDM4CKDM2BKDM6BPHF8 | |
| SCHEMBL17891736 | 0.89 | KDM5B (0.69) | KDM5BKDM4CKDM2BPHF8KDM5A | |
| SCHEMBL17898925 | 0.89 | KDM5B (0.66) | KDM5BKDM4CKDM2BPHF8KDM5A | |
| SCHEMBL17891691 | 0.87 | KDM5B (0.70) | KDM5BKDM4CKDM2BPHF8KDM5A | |
| SCHEMBL17891723 | 0.85 | KDM5B (0.67) | KDM5BKDM4CKDM2BKDM6BKDM5A | |
| SCHEMBL30589263 | 0.85 | KDM5B (0.67) | KDM5BKDM4CKDM2BKDM6BKDM5A | |
| SCHEMBL17891724 | 0.84 | KDM5B (0.68) | KDM5BKDM4CKDM2BPHF8KDM5A | |
| SCHEMBL17891693 | 0.83 | KDM5B (0.57) | KDM5BKDM4CKDM2BKDM6BPHF8 | |
| SCHEMBL19272871 | 0.83 | KDM5B (0.49) | KDM5BKDM4CKDM2BKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |