Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 5/20 | 0.55 |
| ▸ | PAK4 | O96013 | 4/20 | 0.55 |
| ▸ | IGF1R | P08069 | 5/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | PAK3 | O75914 | 1/20 | 0.49 |
| ▸ | PAK2 | Q13177 | 1/20 | 0.49 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26125372 | 1.00 | PAK1 (0.55) | PAK1PAK4IGF1RAURKAPAK3 | |
| SCHEMBL25240513 | 0.96 | PAK1 (0.60) | PAK1PAK4IGF1RAURKAPAK3 | |
| SCHEMBL29593024 | 0.96 | PAK1 (0.60) | PAK1PAK4IGF1RAURKAPAK3 | |
| SCHEMBL29593554 | 0.88 | PAK1 (0.59) | PAK1PAK4IGF1RAURKAPAK3 | |
| SCHEMBL24065152 | 0.88 | PAK1 (0.59) | PAK1PAK4IGF1RAURKAPAK3 | |
| SCHEMBL24350208 | 0.88 | IGF1R (0.51) | PAK1PAK4IGF1RAURKAPAK3 | |
| SCHEMBL24065148 | 0.86 | PAK1 (0.59) | PAK1PAK4IGF1RAURKAPAK3 | |
| SCHEMBL29593099 | 0.86 | IGF1R (0.49) | PAK1PAK4IGF1RAURKAPAK3 | |
| SCHEMBL25245960 | 0.86 | IGF1R (0.49) | PAK1PAK4IGF1RAURKAPAK3 | |
| SCHEMBL30595303 | 0.86 | IGF1R (0.49) | PAK1PAK4IGF1RAURKAPAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490499-A | Modulators of MYC family protooncogene proteins | 纳罗医疗公司 | 2023-07-25 | — | — | CN | disclosed |