SCHEMBL30595937

CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCC(N)=O)C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	13/20	0.74

▸	GCGR	P47871	5/20	0.74

▸	CALCR	P30988	3/20	0.67

▸	GIPR	P48546	8/20	0.66

▸	CRHR1	P34998	1/20	0.65

▸	CRHR2	Q13324	1/20	0.65

▸	NMBR	P28336	1/20	0.65

▸	GRPR	P30550	1/20	0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31146547	0.91	GLP1R (0.74)	GLP1RGCGRCALCRGIPR
SCHEMBL31182680	0.91	GLP1R (0.74)	GLP1RGCGRCALCRNMBRGRPR
SCHEMBL30082666	0.90	GLP1R (0.73)	GLP1RGCGRCALCRNMBRGRPR
SCHEMBL29755703	0.90	GLP1R (0.72)	GLP1RGCGRCALCRNMBRGRPR
SCHEMBL30578647	0.90	GLP1R (0.73)	GLP1RGCGRCALCRNMBRGRPR
SCHEMBL29587969	0.90	GLP1R (0.73)	GLP1RGCGRCALCRNMBRGRPR
SCHEMBL31182675	0.90	CALCR (0.65)	GLP1RGCGRCALCRGIPRNMBR
SCHEMBL30724494	0.90	C5AR1 (0.74)	GLP1RGCGRNMBRGRPR
SCHEMBL30658317	0.89	GLP1R (0.71)	GLP1RGCGRCALCRGIPRCRHR1
SCHEMBL30658354	0.89	CALCR (0.79)	GLP1RGCGRCALCRCRHR1CRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12617815-B2	Barcoded XTEN polypeptides and compositions thereof, and methods for making and using the same	AMUNIX PHARMACEUTICALS, INC. (US)	2026-05-05	—	—	US	disclosed
US-20250051405-A1	EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME	AMUNIX PHARMACEUTICALS, INC.	2025-02-13	—	—	US	disclosed
US-12071456-B2	Extended recombinant polypeptides and compositions comprising same	AMUNIX PHARMACEUTICALS, INC. (US)	2024-08-27	—	—	US	disclosed
CN-117247452-A	Anti-gastrin monoclonal antibodies and uses thereof	英沐生物科技(上海)有限公司	2023-12-19	—	—	CN	disclosed
US-20230324389-A1	COMPOSITIONS AND METHODS RELATED TO ACTIVATABLE THERAPEUTIC AGENTS	AMUNIX PHARMACEUTICALS, INC.	2023-10-12	—	—	US	disclosed
US-20230287040-A1	BARCODED XTEN POLYPEPTIDES AND COMPOSITIONS THEREOF, AND METHODS FOR MAKING AND USING THE SAME	AMUNIX PHARMACEUTICALS, INC.	2023-09-14	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-12617815-B2	Barcoded XTEN polypeptides and compositions thereof, and methods for making and using the same	SPPL2B, PTMS, ANPEP	GLP1R 1777/4885GCGR 3516/4885CALCR 2038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.