SCHEMBL30596267

SCHEMBL30596267

CCCC(O)c1ccccn1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 5/20 0.51
KCNH2 Q12809 1/20 0.51
CYP2D6 P10635 1/20 0.49
KCNE1 P15382 1/20 0.49
KCNJ5 P48544 1/20 0.47
KCNJ3 P48549 1/20 0.47
SCN5A Q14524 1/20 0.47
KCND3 Q9UK17 1/20 0.47
CYP1A2 P05177 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
CHRM2 P08172 2/20 0.44
SCN1A P35498 1/20 0.44
SCN2A Q99250 1/20 0.44
SCN3A Q9NY46 1/20 0.44
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2230732 1.00 KCNA5 (0.51) KCNA5KCNH2CYP2D6KCNE1KCNJ5
SCHEMBL1526122 0.91 KCNA5 (0.50) KCNA5KCNH2CYP2D6KCNE1KCNJ5
SCHEMBL7275282 0.91 KCNA5 (0.50) KCNA5KCNH2CYP2D6KCNE1KCNJ5
SCHEMBL8986648 0.89 KCNA5 (0.49) KCNA5KCNH2CYP2D6KCNE1KCNJ5
SCHEMBL7293012 0.89 KCNA5 (0.49) KCNA5KCNH2CYP2D6KCNE1KCNJ5
SCHEMBL16227724 0.87 KCNA5 (0.47) KCNA5KCNH2CYP2D6KCNE1KCNJ5
SCHEMBL28331181 0.87 KCNA5 (0.47) KCNA5KCNH2CYP2D6KCNE1KCNJ5
Hydrochloric Acid SCHEMBL8608055 0.87 KCNA5 (0.47) KCNA5KCNH2CYP2D6KCNE1KCNJ5
SCHEMBL6000906 0.87 KCNA5 (0.47) KCNA5KCNH2CYP2D6KCNE1KCNJ5
SCHEMBL31744336 0.86 KCNA5 (0.52) KCNA5KCNH2CYP2D6KCNE1KCNJ5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118510877-A Cleaning composition for pretreatment of metal substrates, method for the production thereof and use thereof 巴斯夫涂料有限公司 2024-08-16 CN disclosed
CN-118255685-A Tricyclic compound, pharmaceutical composition and application thereof 珂阑(上海)医药科技有限公司 2024-06-28 CN disclosed
CN-116836162-A Pyrazolo [4,3-c ] pyridine compound or pharmaceutically acceptable salt thereof and application thereof 南方医科大学 2023-10-03 CN disclosed