Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532775 | 1.00 | HTR2C (0.37) | HTR2CDPP4BACE1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL29995070 | 0.98 | HTR2C (0.36) | HTR2CDPP4BACE1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL7874218 | 0.98 | HTR2C (0.36) | HTR2CDPP4BACE1ADRA2AADRA2B | |
| SCHEMBL29087329 | 0.89 | HTR2C (0.36) | HTR2CDPP4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28672682 | 0.88 | BACE1 (0.40) | BACE1ADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL29087317 | 0.87 | HTR2C (0.35) | HTR2CDPP4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18742523 | 0.84 | BACE1 (0.38) | BACE1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL1194976 | 0.84 | HTR2C (0.39) | HTR2CHDAC6HTR2A | |
| Hydrochloric Acid SCHEMBL2780103 | 0.83 | HTR2C (0.38) | HTR2CHDAC6HTR2A | |
| SCHEMBL22357274 | 0.83 | HTR2C (0.35) | HTR2CDPP4AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116806217-A | Substituted cyclic modulators of protein phosphatase 2A (PP 2A) and methods of use thereof | 拉帕塔疗法公司 | 2023-09-26 | — | — | CN | disclosed |