Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 1.00 |
| ▸ | JAK1 | P23458 | 2/20 | 1.00 |
| ▸ | JAK2 | O60674 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zasocitinib SCHEMBL20697064 | 1.00 | TYK2 (1.00) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| Zasocitinib SCHEMBL20678921 | 1.00 | TYK2 (1.00) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| Zasocitinib SCHEMBL20678925 | 1.00 | TYK2 (1.00) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| Zasocitinib SCHEMBL20678885 | 1.00 | TYK2 (1.00) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| Zasocitinib SCHEMBL31710036 | 1.00 | TYK2 (1.00) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| Zasocitinib SCHEMBL30895721 | 0.96 | TYK2 (0.92) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| Zasocitinib SCHEMBL30895694 | 0.96 | TYK2 (0.92) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL20697069 | 0.94 | TYK2 (1.00) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL20687868 | 0.94 | TYK2 (1.00) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL20687862 | 0.94 | TYK2 (1.00) | TYK2JAK1JAK2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025107861-A1 | CRYSTAL FORM OF ZASOCITINIB, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州科睿思制药有限公司 | 2025-05-30 | — | — | WO | disclosed |
| WO-2025062372-A1 | TYK2 INHIBITORS FOR USE IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-03-27 | — | — | WO | disclosed |
| EP-4499104-A1 | TYK2 INHIBITORS AND USES THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2025-02-05 | — | — | EP | disclosed |
| CN-118973583-A | TYK2 inhibitor and application thereof | 武田药品工业株式会社 | 2024-11-15 | — | — | CN | disclosed |
| CN-118084920-A | Five membered heteroaromatic pyrimidine-3-carboxamide derivatives, compositions and uses thereof | 镇江圣安医药有限公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023183901-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2023-09-28 | — | — | WO | disclosed |