SCHEMBL30598936

SCHEMBL30598936

CC1CC(c2cccc(Br)c2)(c2nncn2C)C1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CBLB Q13191 20/20 0.57
CBL P22681 18/20 0.57
CBLC Q9ULV8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22850264 1.00 CBLB (0.57) CBLBCBLCBLC
SCHEMBL22849886 1.00 CBLB (0.57) CBLBCBLCBLC
SCHEMBL30520987 0.91 CBLB (0.49) CBLBCBLCBLC
SCHEMBL22832670 0.89 CBLB (0.46) CBLBCBLCBLC
SCHEMBL25173620 0.89 CBLB (0.46) CBLBCBLCBLC
SCHEMBL25179668 0.89 CBLB (0.46) CBLBCBLCBLC
SCHEMBL25311764 0.89 CBLB (0.47) CBLBCBLCBLC
SCHEMBL22851384 0.89 CBLB (0.46) CBLBCBLCBLC
SCHEMBL25192736 0.89 CBLB (0.47) CBLBCBLCBLC
SCHEMBL25311818 0.89 CBLB (0.47) CBLBCBLCBLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4490152-A1 ACTIVATORS OF EFFECTOR T CELLS Orum Therapeutics Inc. (KR) 2025-01-15 EP disclosed
WO-2024255762-A1 CBL-B INHIBITOR 上海齐鲁制药研究中心有限公司 2024-12-19 WO disclosed
CN-117858865-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 CN disclosed
WO-2023170608-A1 ACTIVATORS OF EFFECTOR T CELLS ORUM THERAPEUTICS, INC. (KR) 2023-09-14 WO disclosed