Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 11/20 | 0.48 |
| ▸ | RXRA | P19793 | 10/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 10/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24403238 | 1.00 | NR1H2 (0.48) | NR1H2RXRANR1H3BACE1KDM1A | |
| SCHEMBL30599281 | 1.00 | NR1H2 (0.48) | NR1H2RXRANR1H3BACE1KDM1A | |
| SCHEMBL24403239 | 1.00 | NR1H2 (0.48) | NR1H2RXRANR1H3BACE1KDM1A | |
| SCHEMBL26312430 | 0.90 | NR1H2 (0.48) | NR1H2RXRANR1H3BACE1 | |
| SCHEMBL6521416 | 0.90 | NR1H2 (0.51) | NR1H2RXRANR1H3BACE1 | |
| SCHEMBL3664778 | 0.90 | NR1H2 (0.51) | NR1H2RXRANR1H3BACE1 | |
| SCHEMBL26312431 | 0.90 | NR1H2 (0.48) | NR1H2RXRANR1H3BACE1 | |
| SCHEMBL25240372 | 0.90 | NR1H2 (0.51) | NR1H2RXRANR1H3BACE1 | |
| SCHEMBL24451647 | 0.88 | BACE1 (0.53) | NR1H2RXRANR1H3BACE1 | |
| SCHEMBL3724868 | 0.88 | BACE1 (0.53) | NR1H2RXRANR1H3BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969957-A | Indazole compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116813697-A | Halogenated benzene ring-spiro compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-09-29 | — | — | CN | disclosed |