Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124701 | 1.00 | BTK (0.49) | BTKLCKDGAT2CYP11B1CYP11B2 | |
| SCHEMBL29418480 | 0.90 | BTK (0.48) | BTKLCKDGAT2MEN1KMT2A | |
| SCHEMBL29418414 | 0.90 | BTK (0.48) | BTKLCKDGAT2 | |
| SCHEMBL25214221 | 0.90 | BTK (0.48) | BTKLCKDGAT2MEN1KMT2A | |
| SCHEMBL25208887 | 0.90 | BTK (0.48) | BTKLCKDGAT2 | |
| SCHEMBL25267674 | 0.90 | BTK (0.49) | BTKLCKDGAT2 | |
| SCHEMBL25224081 | 0.90 | BTK (0.48) | BTKLCKDGAT2 | |
| SCHEMBL25260482 | 0.90 | BTK (0.48) | BTKLCKDGAT2 | |
| SCHEMBL29418437 | 0.90 | BTK (0.49) | BTKLCKDGAT2 | |
| SCHEMBL29418522 | 0.90 | BTK (0.48) | BTKLCKDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |