Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733182 | 1.00 | MEN1 (0.54) | MEN1KMT2ANPC1MITFRAB9A | |
| Benzene SCHEMBL10464328 | 0.86 | NOTUM (0.70) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL6199079 | 0.84 | NOTUM (0.72) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL5619699 | 0.83 | NOTUM (0.71) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL31220020 | 0.83 | NOTUM (0.71) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL6195455 | 0.81 | NPC1 (0.84) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL10836725 | 0.81 | NPC1 (0.58) | MEN1KMT2ANPC1MITFRAB9A | |
| Hydrochloric Acid SCHEMBL6197508 | 0.80 | NPC1 (0.57) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL17765508 | 0.80 | MEN1 (0.53) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL28956480 | 0.77 | AKR1B1 (0.40) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583977-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024052512-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-14 | — | — | WO | disclosed |
| CN-116891465-A | N-substituted quinolinone compounds, preparation method and application thereof | 苏州旺山旺水生物医药有限公司 | 2023-10-17 | — | — | CN | disclosed |