Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 19/20 | 0.70 |
| ▸ | BCL2 | P10415 | 11/20 | 0.69 |
| ▸ | MDM4 | O15151 | 1/20 | 0.65 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | BID | P55957 | 1/20 | 0.65 |
| ▸ | BAX | Q07812 | 1/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | ASPH | Q12797 | 1/20 | 0.65 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.65 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.65 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.65 |
| ▸ | BAD | Q92934 | 1/20 | 0.65 |
| ▸ | BBC3 | Q9BXH1 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26682294 | 1.00 | BCL2L1 (0.70) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540181 | 0.96 | BCL2L1 (0.74) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540734 | 0.94 | BCL2L1 (0.73) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540976 | 0.94 | BCL2L1 (0.75) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL26682060 | 0.94 | BCL2L1 (0.69) | BCL2L1BCL2 | |
| SCHEMBL1540421 | 0.93 | BCL2L1 (0.68) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540200 | 0.93 | BCL2L1 (0.73) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL26681275 | 0.92 | BCL2L1 (0.66) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540482 | 0.92 | BCL2L1 (0.68) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL26681846 | 0.91 | BCL2L1 (0.67) | BCL2L1BCL2MDM4BCL2L11TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |
| CN-116829524-A | Method for alkylating acidic functional groups | 中外制药株式会社 | 2023-09-29 | — | — | CN | disclosed |