Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 14/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19586788 | 1.00 | CRBN (0.55) | CRBNDDB1GAATDP1IKZF3 | |
| SCHEMBL19586839 | 0.83 | CRBN (0.54) | CRBNDDB1TDP1IKZF3ALDH1A1 | |
| SCHEMBL30969004 | 0.81 | CRBN (0.49) | CRBNDDB1TDP1IKZF3ALDH1A1 | |
| SCHEMBL29264313 | 0.81 | CRBN (0.49) | CRBNDDB1TDP1IKZF3ALDH1A1 | |
| SCHEMBL19586295 | 0.81 | CRBN (0.55) | CRBNDDB1TDP1IKZF3ALDH1A1 | |
| SCHEMBL30600402 | 0.81 | CRBN (0.55) | CRBNDDB1TDP1IKZF3ALDH1A1 | |
| SCHEMBL26250286 | 0.80 | CRBN (0.55) | CRBNDDB1GAATDP1IKZF3 | |
| SCHEMBL1895103 | 0.79 | GAA (0.60) | GAATDP1ALDH1A1 | |
| SCHEMBL4383909 | 0.76 | GAA (0.57) | GAATDP1ALDH1A1 | |
| SCHEMBL19606336 | 0.76 | CRBN (0.56) | CRBNDDB1TDP1IKZF3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621664-B | Novel piperidine-2, 6-dione derivatives and uses thereof | 韩国化学研究院 | 2023-08-01 | — | — | CN | disclosed |